The Department of Botany was established in 1923. The Department has the honor of having Botanists of International repute on the staff namely Professor L. A. Ajrekar (1923-1930), Professor R. H. Dastur (1931-1935), Professor F. R. Bharucha (1936-1956), Professor Mrs. E. Gonzalves (1956-1962), Professor V. R. Dnyansagar (1963-1971), Dr. V. D. Tilak (1971-1974 ,1976-1983), Professor Mrs. S. Chitaley (1974-1976) and Professor B. B. Chaphekar (1983-1987), Professor F. R. Bharucha was the Director of The Institute of Science from 1954-1959. He has made substantial contribution to grassland and desert ecology. It won him worldwide recognition. He was the President of Indian Ecological society; Vice President of International Botanical Congress & was commissioned by UNESCO to write the report on ecological research. He served as UN expert in Botany at University of Syria. Prof. V. R. Dnyansagar has earned himself reputation of a world known Cyto-geneticist. Prof. Mrs. Chitale, a known Paleobotanist, has developed a technique of preserving plant material, popularly known Chitale method. Dr. V. D. Tilak has designed an equipment to collect the samples of Arial flora, popularly known as Tilak Sampler. The pioneer work of Dr. V. D. Tilak and his group on Floral and nodal anatomy is cited in the work of world-renowned Botanists, Arthur Cronquists and Armen Thakhtajan. Professor S. B. Chaphekar is known for his contribution in Ecology. The Department is equipped with sophisticated instrumental facilities and well established Plant Cell Culture lab. The Department conducts three specializations, Molecular Biology and Plant Biotechnology, Plant Physiology and Biochemistry and Environmental Botany in the core Subject, Botany. The Faculty is actively involved in the Research activities. Professor Vijay D. Mendhulkar is presently heading the Department. In-vitro Mutagenesis, In–vitro techniques and Secondary Plant Metabolites, Nanobiotechnology, Chemical Fingerprinting, Tissue culture studies, Fungal enzyme studies and Ecological Studies are the current Research areas of interest for Ph.D. programmes in the Department.